specimen
#0374
status: complete
- sequence
- DEKRRKDEQNNSTTSAGVILM
- from wallet
- 2A2WXH7JzGaf535apM2U8cPFbUfyCUe8prNrDrgsfKcf
- amount paid
- 0 SOL
- transaction
- 4YUx8owPyH8Dxnki46XbcxAVZrqvVx9Z5c5GpEmFCzD5wZKSvAjbbvDgyBMSNXCeB6LBJeg6WatjMyah11fdf8YV ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence62%confidence 52% · band 50-74%ESMFold esmatlas-esmfold-v1disorder estimate67%confidence 52% · band 55-79%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk22%confidence 56% · band 11-33%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden24%confidence 84% · band 20-28%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk0%confidence 84% · band 0-4%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk18%confidence 56% · band 7-29%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_6571ec09c1774fa6a01891deffd27786seq sha256: dc0bec13029ea8537806f3571387fce1dc65e34f11a43b55f1f008635ad2f490report sha256: f87286e492b8c2c6e956214a313e7cd66e4a6e138ef113146e3b6cc1bfe01599pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no structure at all. starts with a charged storm of acids and bases neutralizing each other, then trails off into polar nothing and a hydrophobic tail. like three different peptides got stitched together and gave up.”
- device photo
- created
- Wed, 17 Jun 2026 20:03:12 GMT
- completed
- Wed, 17 Jun 2026 20:17:49 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 67% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.