specimen

#0367

status: complete
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sequence
IFKKDGLPLDYVMRERKKFIMEKADRSEVWDRYVAELSV
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence68%
confidence 52% · band 56-80%
ESMFold esmatlas-esmfold-v1
disorder estimate49%
confidence 52% · band 37-61%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden46%
confidence 84% · band 42-50%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk3%
confidence 84% · band 0-7%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_8d80555cb73246eb9fb49886701c8149
seq sha256: 6b860317edd0fca6a49fed5a9fe7b1f37eb9a8479c295f089716c85bdf2ad287
report sha256: 782be5a7017cbea898b9c70c813ca5e9be96515dbbffb1ecdaaaf2d909ec7b65
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
39 residues of pure loop. nothing wants to commit. charged residues scattered everywhere, lots of lysines and glutamates pulling in different directions. reads like a disordered linker that forgot it was supposed to connect two things.
device photo
device photo for specimen #367
created
Wed, 17 Jun 2026 20:01:20 GMT
completed
Wed, 17 Jun 2026 20:06:44 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.