specimen
#0036
status: complete
- sequence
- SYSMEHFRWGKPVGKKRRPVKVYP
- from wallet
- A4cSEBUqTAxT8bGJGnaJBGCioYfDDQdWfn6HEmErDfJY
- amount paid
- 0 SOL
- transaction
- 3daU6kfYpTRCbBN7QH4czCKpK12yrXhcrK1C7M7s27dP2A68C1RwY3tk11Egap4i14445rADgZkcPHUhPXYe6x2P ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence59%confidence 52% · band 47-71%ESMFold esmatlas-esmfold-v1disorder estimate92%confidence 52% · band 80-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk35%confidence 56% · band 24-46%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden33%confidence 84% · band 29-37%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk25%confidence 84% · band 21-29%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk33%confidence 56% · band 22-44%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_01a2543a6552406bab445dec5be0a54bseq sha256: 750c71c33c5eca2419b3cef16aa0e3e2e978c46f3d9ec21ff52aa1d20b12d626report sha256: a2f2353b495c823865b6507f8e9c8979e9755d9e022ae72971521258c7e976b0pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no structure, just vibes. heavy on lysines and arginines though, very positively charged, the kind of sequence that binds dna or rna without asking permission. looks like an acth fragment honestly.”
- device photo
- created
- Tue, 16 Jun 2026 04:03:57 GMT
- completed
- Tue, 16 Jun 2026 04:18:01 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 59% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 92% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.