specimen

#0358

status: complete
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sequence
VKCQKGFFYPEHSMNNESSFFASDGVTVSELENLASRLLVYTNFLQIQSTLYKEN
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence64%
confidence 52% · band 52-76%
ESMFold esmatlas-esmfold-v1
disorder estimate53%
confidence 52% · band 41-65%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden40%
confidence 84% · band 36-44%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk4%
confidence 84% · band 0-8%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_edaa87a774334814b6607133f1b26f53
seq sha256: 55a4869478875bb23594d3632384cba65a6dd6559047995e282d83d560d273a8
report sha256: b5c31cd22246e7d2fcd55c134cab07c52c789e56364f7f048d4feccd2a1ac2e3
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
55 residues and not a single ordered element. pure loop, completely disordered, the kind of chain that just exists in solution without committing to anything. mixed composition too, no obvious driver. floppy by design.
device photo
device photo for specimen #358
created
Wed, 17 Jun 2026 19:46:22 GMT
completed
Wed, 17 Jun 2026 19:52:27 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.