pepscanPepScan
specimen

#0356

status: complete
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sequence
APADLGKWTHTVGFRPLIIIGPGNNKLATSKACHRETVEPRTVLHFGKFDSVD
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence49%
confidence 52% · band 37-61%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden36%
confidence 84% · band 32-40%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk4%
confidence 84% · band 0-8%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_b9135bc063da49098e96db4433bc4a92
seq sha256: 9467e08d542e77b346af65cbd7cc2c9c07e3fab24184808459980a4654f7eee5
report sha256: bbe2fd4fdf597e301317cdfa364a3cf0ba3a0a87790e6ba4cf1f34409be82baa
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“all loop. 53 residues of pure noodle, not a single ordered segment to grab onto. reads like a fragment that lost its scaffold on the way over.”
device photo
device photo for specimen #356
created
Wed, 17 Jun 2026 19:45:14 GMT
completed
Wed, 17 Jun 2026 19:49:27 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 49% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.