pepscanPepScan
specimen

#0344

status: complete
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sequence
IGGIVTRTELAGRTEETARGVRQFPWFTNSL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence58%
confidence 52% · band 46-70%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden36%
confidence 84% · band 32-40%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk3%
confidence 84% · band 0-7%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
audit trail
run: run_0fb9b5a83db74fb788ea480114555de0
seq sha256: 26ccf90445ec443d83684bea76db05a31f20a63602018b9aa3792455bfd2fdbc
report sha256: 903c00d247b5a21fd43523df8e26d475eaa75941f4cc2b89367917bd95e31ff7
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“31 residues of pure loop. no structure at all, just a long floppy ribbon flopping around the chamber. composition is mixed, slightly hydrophobic in patches, but nothing commits. reads like a linker that forgot it was supposed to connect to something.”
device photo
device photo for specimen #344
created
Wed, 17 Jun 2026 17:33:31 GMT
completed
Wed, 17 Jun 2026 17:53:08 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 58% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.