specimen

#0342

status: complete
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sequence
EDEHFTHKETRPVATAGSLKSVAARGLRYLVLEIIFFRKSACPTRGSAEAPD
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence47%
confidence 52% · band 35-59%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk33%
confidence 56% · band 22-44%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden39%
confidence 84% · band 35-43%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk2%
confidence 84% · band 0-6%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_3a3caba89a67430c9c010784c637d359
seq sha256: a62f2b2f2d291a2b1f286a9be22e1fef68cc5f2bc9ebb50317c129d3fa33c6b6
report sha256: 4b2653a28eb8326434fc61868f7d45311d5251bc6886a1831db84a4880816a2f
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
52 residues of pure loop. no helix, no sheet, nothing committing to anything. mostly charged and polar up front, then a hydrophobic streak in the middle that should have folded but didn't. disappointing in an interesting way.
device photo
device photo for specimen #342
created
Wed, 17 Jun 2026 17:32:15 GMT
completed
Wed, 17 Jun 2026 17:50:17 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 47% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.