specimen
#0341
status: complete
- sequence
- MFGAVACPQHLTPNHKEVPYDLARVGLNERVREGRLPNQGLRI
- from wallet
- CRJFU5HfNsiGofAQ152DJLLqg1FW5mhJj9arTrpE9zyi
- amount paid
- 0 SOL
- transaction
- 3TL9XaygjXACZ9yGSsQM9NyFUXHQKDhTqCVR5X8yiPgfqcNoDpi6PVxt68Zi1qVZXUz5f5495MrGQEtLhHaSVnAP ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence47%confidence 52% · band 35-59%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden37%confidence 84% · band 33-41%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk5%confidence 84% · band 1-9%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk28%confidence 56% · band 17-39%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_b6aef03d241248d8b2a50585ae085c86seq sha256: aa500abcf01d15a046c0815cc9a3bc6f61bb57f8ad0334977b43359f74673b07report sha256: f16046aa196ca1a16e582458ac879e771068c52ec89a21dfd646c39ab7b173fepepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no commitment. 43 residues of pure floppiness, like it forgot to fold on the way over. composition is all over the place too, charged residues scattered with no real plan.”
- device photo
- created
- Wed, 17 Jun 2026 17:31:40 GMT
- completed
- Wed, 17 Jun 2026 17:48:52 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 47% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.