specimen

#0340

status: complete
download JSONdownload PDFchat with report
sequence
VNLGVRSTEIDAIAKCFQNSEFHSLDAAVVV
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence64%
confidence 52% · band 52-76%
ESMFold esmatlas-esmfold-v1
disorder estimate55%
confidence 52% · band 43-67%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk34%
confidence 56% · band 23-45%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden48%
confidence 84% · band 44-52%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk7%
confidence 84% · band 3-11%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_6a18d807a42b4b1d8c66a2992e3c6ff2
seq sha256: 25742d7ddcd13e5821da0d33d6fc4594066082a70fce336f56b231db5d08eaf3
report sha256: fb936f291acfeb75048d8ad083e2456aa1d4db9ef6258250db5b2633ef40b396
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
100% loop, zero structure. 31 residues of pure indecision, just flopping around with nothing to hold onto. shame, because there's a decent hydrophobic core hiding in there if it ever committed to a fold.
device photo
device photo for specimen #340
created
Wed, 17 Jun 2026 17:31:03 GMT
completed
Wed, 17 Jun 2026 17:47:26 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.