#0337
- sequence
- GYILHELVFSLYAPDMVSTDVNNGSFDHCPSGTREDGNASWIMSY
- from wallet
- 6F4J6AdT5iQx4ExeN7JFE7EEM6fJ1XJ3DRUHT56gMfWF
- amount paid
- 0 SOL
- transaction
- 5uR1EVPpVfYegAgPAwGa7WV7opmLrp9k7KJgQCPPG3EQCFgFb6CfbCUmToB9cGR2Unro3TGh7byawmatVbshi2nB ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence45%confidence 52% · band 33-57%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk36%confidence 56% · band 25-47%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden40%confidence 84% · band 36-44%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk11%confidence 84% · band 7-15%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_7dd7092fdba449709aefb1dc0cc49812seq sha256: 91f43dabeadcaf3052dca2377e2594b9b5537cecd23383aefeb72b579c586f5areport sha256: 4f608dd8f79ba503dbedb73d70f1524046d74661f24f7944cb3d646d1bd26968pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “45 residues of pure loop. no helix, no sheet, nothing committing to anything. reads like a peptide that gave up halfway through deciding what to be.”
- device photo
- created
- Wed, 17 Jun 2026 17:29:15 GMT
- completed
- Wed, 17 Jun 2026 17:42:52 GMT
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G), potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 3 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 45% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)