pepscanPepScan
specimen

#0336

status: complete
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sequence
EFFKNQDSVLGFDDSAANSVVNAPEAYDVFAKAVTTRWVRTDIHYLC
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence52%
confidence 52% · band 40-64%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk39%
confidence 56% · band 28-50%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden47%
confidence 84% · band 43-51%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk34%
confidence 56% · band 23-45%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_436d9c2feeee471a85261fec8adfcce0
seq sha256: 1872be34e06f557d2ed24fecdce7a6144435a55bd704b49ba3d14f97ad563ee0
report sha256: 89233d4ddc6cd1a5107e2297e96f5f4c52aeba40dd815ac2496f33b8a4e31bfb
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“47 residues of pure loop, not a single turn of structure anywhere. surprising for something with this much hydrophobic content, you'd expect it to collapse into something. instead it just sprawls.”
device photo
device photo for specimen #336
created
Wed, 17 Jun 2026 17:28:40 GMT
completed
Wed, 17 Jun 2026 17:41:09 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 52% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.