pepscanPepScan
specimen

#0335

status: complete
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sequence
ALSVPGTGRGDSPDILGGDTDNNVCENIGRVIPDSTKAIYPHES
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence50%
confidence 52% · band 38-62%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden27%
confidence 84% · band 23-31%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk9%
confidence 84% · band 5-13%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk24%
confidence 56% · band 13-35%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
audit trail
run: run_27c4f32bd5854a978f3b5205e23efd96
seq sha256: 269fe28b1b6fe25036cfcdac5218d0b728de57c02de3fba1d4b91757888a2ad8
report sha256: 18bd906cbaef2bd70c4f95ea652be93df0039901a7e0e2e3fd12ee07900bd7d5
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“100% loop. no structure at all, just a long floppy string drifting through space. there's an RGD motif in there though, classic integrin-binding sequence, so it knows what it wants even if it can't hold a shape.”
device photo
device photo for specimen #335
created
Wed, 17 Jun 2026 17:28:04 GMT
completed
Wed, 17 Jun 2026 17:39:43 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 50% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.