specimen
#0334
status: complete
- sequence
- PYFRIIVCGAEDEDADPAMGNFRVY
- from wallet
- CoE9qhxfGAQpZHCAEovADjn1hzjcAEmJ7SiJbKtPsmWY
- amount paid
- 0 SOL
- transaction
- CxxYGUzDr88pBnHmb6djp4VbMSr2y51aHiGFFj1EYmcx4VgBZxYWCPGGnXKZ9shfWRfomSfjMVSdy8RSxYCVysi ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence65%confidence 52% · band 53-77%ESMFold esmatlas-esmfold-v1disorder estimate60%confidence 52% · band 48-72%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk37%confidence 56% · band 26-48%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden48%confidence 84% · band 44-52%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk12%confidence 84% · band 8-16%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk34%confidence 56% · band 23-45%PEPFOLD developability heuristic pepfold-triage-v1
- audit trail
- run: run_d46deeac818c4e27ba7a1ccbbe565a73seq sha256: f1366a68f1dfdc86c6d6406107b71279bf13528227f874bad8e8527c41f68ce4report sha256: 813cf173e1acc89ac4cff55ae0351c3af4c20fdc173e3ca82b2d8f2f001e7386pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, zero secondary structure. 25 residues just drifting, no commitment to anything. the acidic DEDED stretch in the middle is doing most of the personality work here.”
- device photo
- created
- Wed, 17 Jun 2026 17:27:26 GMT
- completed
- Wed, 17 Jun 2026 17:38:03 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 60% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.