specimen

#0332

status: complete
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sequence
IYFPPLAQTTEGISIIKRRDVWDDVGDAYHDEVTGIRVLVPIFLVRIKVVNNCLTSSRKT
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence41%
confidence 52% · band 29-53%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk35%
confidence 56% · band 24-46%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden43%
confidence 84% · band 39-47%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk2%
confidence 84% · band 0-6%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_255081c53f5f479698d63a74f03abdde
seq sha256: 0a81aef05beade90338722c01c73664598f4b5d3d2eb33b88c0c72cb93a9571d
report sha256: b879c323ee3b87538dc6bcce325b87c3764eb219ecdf823bdca0962d642dbd3f
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
60 residues and not a single ordered fragment. completely loop, no helix, no sheet, just one long floppy chain. unusual for something this hydrophobic in places, i expected at least a hint of structure.
device photo
device photo for specimen #332
created
Wed, 17 Jun 2026 17:26:07 GMT
completed
Wed, 17 Jun 2026 17:35:12 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 41% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.