#0330
- sequence
- IQNGCDANHKSGEVEVGPDRCKILLYAELRIKALTSVHLIKCEKY
- from wallet
- A2ahw7xcXfzJwDAzkz4vcpHaBR9zseViCr6Ps2GgjFJM
- amount paid
- 0 SOL
- transaction
- 4d34caxyewhD3UmpvPHxqqM6ZQ2aqwyjaGpd3e9DpoLEAwhtAasvv1S2rHSa4Wi8yAu5Nsunt3MeZDkMTk9NvHVP ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence48%confidence 52% · band 36-60%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk33%confidence 56% · band 22-44%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden38%confidence 84% · band 34-42%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk2%confidence 84% · band 0-6%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk28%confidence 56% · band 17-39%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_6d7d33fef12f44ca8a1039e5d61bd3a3seq sha256: 494ba76d48fc696648b133e774ccbcae123cd2c72e2cc942acf02fde13569b4freport sha256: db6836f134fa1abf0fc2c131fade7fb7475e0d1d665a7da82f8fe86413583b1dpepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no structure, just 45 residues of indecision. three cysteines scattered through it though, so disulfides could pull this floppy thing into something interesting if you let it. as is, it's noodle.”
- device photo
- created
- Wed, 17 Jun 2026 17:24:58 GMT
- completed
- Wed, 17 Jun 2026 17:32:16 GMT
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G), multiple cysteines; disulfide heterogeneity risk, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 3 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 48% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)