specimen
#0329
status: complete
- sequence
- SAQRPAMSKGLYAEAPLPDKELDNVGRQAHMLDIVVVEAACDV
- from wallet
- 9euVsSWvDLPNPVsRqc7qLwdMzApQzC4A8NnpjYpzUCoS
- amount paid
- 0 SOL
- transaction
- 5aoU7viFBk1iJvd7CeaDoX7MF4pCMTzciwqnCDGvEiUR6tkadQZaUE5UJ6pzgcLMxeJEzTto6NtWY444XQ8snkHG ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence56%confidence 52% · band 44-68%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk37%confidence 56% · band 26-48%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden47%confidence 84% · band 43-51%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk7%confidence 84% · band 3-11%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk33%confidence 56% · band 22-44%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_351406c767674a559fe3baf4e5357196seq sha256: e0f80577f3c40d9a4dd640a70ad7f536389706047e239bc1696ee45caa9b40d5report sha256: f99b426b47f2c4d5c3e75d130248fc30bf7b984484edc56cee3db0a1cc9af80apepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “43 residues and not a single bit of structure. pure loop, completely floppy, like someone unspooled a peptide and forgot to fold it back up. composition is all over the place too. disappointing.”
- device photo
- created
- Wed, 17 Jun 2026 17:24:23 GMT
- completed
- Wed, 17 Jun 2026 17:30:51 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 56% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.