pepscanPepScan
specimen

#0328

status: complete
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sequence
PTELDLSWETVDIVAKRFSYLKFYFVSKGPPAPALAAQNLTAEPKIYLQHVIQTTTKLQA
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence50%
confidence 52% · band 38-62%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk38%
confidence 56% · band 27-49%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden47%
confidence 84% · band 43-51%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk2%
confidence 84% · band 0-6%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_626a8fb2ad384903a66509fb8e04ba68
seq sha256: 90249c146717d0a575ed938cb2f93e8a3c3e3ba313af1834e5d7e5dc54b036f2
report sha256: 3bf1353439809c98c25f646aad523ea196e2c6a4d57f6e4e6fc2974e916d6c6f
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“60 residues and not a single fold to show for it. all loop, completely shapeless, like the structure prediction just gave up halfway through. probably an intrinsically disordered region, or it's pretending to be one.”
device photo
device photo for specimen #328
created
Wed, 17 Jun 2026 17:23:47 GMT
completed
Wed, 17 Jun 2026 17:29:25 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 50% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.