specimen

#0325

status: complete
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sequence
FLPWPSGSLVIDWISALALHATTDLRTKFFLYSDRHYYW
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence52%
confidence 52% · band 40-64%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk44%
confidence 56% · band 33-55%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden54%
confidence 84% · band 50-58%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk37%
confidence 56% · band 26-48%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
audit trail
run: run_70450185c4ef405096345da3bf0c2e09
seq sha256: 57cfc9a449648719c93e60149fabefb0ddd6e10ba4f790a1f668eb023015b115
report sha256: 6c31fb7cb61e9d6709bad5d966ffe61f7bea0ae1419335714575185d69fe4e54
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
39 residues and not a single ordered fragment. all loop, completely floppy, like it gave up halfway through deciding what to be. composition is busy though, aromatics and charges scattered around with no apparent plan.
device photo
device photo for specimen #325
created
Wed, 17 Jun 2026 17:21:58 GMT
completed
Wed, 17 Jun 2026 17:25:06 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 52% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.