pepscanPepScan
specimen

#0312

status: complete
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sequence
RVQESNLRTESGTLIYVEIVSRGVYDNQLEEKDVTALSVTGVDNHGKTPNE
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence48%
confidence 52% · band 36-60%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden31%
confidence 84% · band 27-35%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_5e35499e0cd84f2eb972d5c200e9bb84
seq sha256: 41030b8bc48986bbc25ca59c4c7053be2f3f24505ea7ab89b2e0ad2e69883b87
report sha256: 925413f63ca793cd6ac6aac393c5724d49361b2f8d2b879c44c711bf187f8026
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“100% loop. no helix, no sheet, just 51 residues of pure indecision. reads like a fragment that fell off something larger and forgot how to fold on its own.”
device photo
device photo for specimen #312
created
Wed, 17 Jun 2026 16:21:58 GMT
completed
Wed, 17 Jun 2026 16:39:19 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 48% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.