specimen
#0311
status: complete
- sequence
- KAMDELIPGAWEFTLTPDLENCFVFEESLTGDAYISEVEVLPSKITGNRITN
- from wallet
- CRJFU5HfNsiGofAQ152DJLLqg1FW5mhJj9arTrpE9zyi
- amount paid
- 0 SOL
- transaction
- 4vGhMGeRDKw3Rd8ajh5e3oogwfkfyFTkK4ehfP7rh3uXDvfcddNJaTBRiZnuH5VzUJbpfxZzp61v6ocZdGv5ztDY ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence50%confidence 52% · band 38-62%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk36%confidence 56% · band 25-47%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden40%confidence 84% · band 36-44%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk14%confidence 84% · band 10-18%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- synthesis hints
- - sequence length >45 aa may reduce synthesis yield
- audit trail
- run: run_8e249ce6f0f54c709903654255a8cb8dseq sha256: de71aa3eac1151a2cb72baa0e74aff6cc954264ef847c84ed598c2819fda40c7report sha256: 42ab8794d278bc1ef584d53c4488c28a54b97290b52b10e08c49f36f4af934bfpepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “52 residues of pure loop. no helix, no sheet, just a long floppy ribbon doing whatever it wants. composition is all over the place too, like someone shook the amino acid jar and called it a peptide.”
- device photo
- created
- Wed, 17 Jun 2026 16:21:23 GMT
- completed
- Wed, 17 Jun 2026 16:37:55 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 50% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.