specimen
#0310
status: complete
- sequence
- QDADPRAEIEILGHRFSVPMGYGCKDFG
- from wallet
- BzBomhaACTVa1RLCkQE7kyLgfLGKdUysrREmbeGzfndA
- amount paid
- 0 SOL
- transaction
- 4fHaQDH6xFqRRgR5scmEmBAUNVFnT6Xagp333hWuBHLUNk73nrM21Cudv588AdyPLPpfNMC7yoDBZVVtjpurCsgU ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence62%confidence 52% · band 50-74%ESMFold esmatlas-esmfold-v1disorder estimate68%confidence 52% · band 56-80%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk29%confidence 56% · band 18-40%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden36%confidence 84% · band 32-40%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk7%confidence 84% · band 3-11%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk26%confidence 56% · band 15-37%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_25eddd8a336541d3b40c6204a1761241seq sha256: 99c5d822eade5b9848ca795c5404a0c72d169c350c6a79be823629d4fbdf5303report sha256: a3cbfbd296104d3a28ae33f83e0d7ad0f51cc1f51382ba774805be5314ee1e9epepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no commitment. 28 residues of pure floppiness, no helix or sheet anywhere, just charged and polar stuff drifting around. reads like a flexible linker that forgot it was supposed to connect something.”
- device photo
- created
- Wed, 17 Jun 2026 16:20:47 GMT
- completed
- Wed, 17 Jun 2026 16:36:29 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 68% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.