specimen

#0296

status: complete
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sequence
PEYIGTASCSYVLLERDTSEQSA
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence66%
confidence 52% · band 54-78%
ESMFold esmatlas-esmfold-v1
disorder estimate91%
confidence 52% · band 79-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk34%
confidence 56% · band 23-45%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden35%
confidence 84% · band 31-39%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk13%
confidence 84% · band 9-17%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk30%
confidence 56% · band 19-41%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: predicted disorder is elevated
audit trail
run: run_6551acad09e440aea4312ae923048ea4
seq sha256: 2060c09c5af89a62ab8afebb4f567324649da16ddce4408f837d23d8528c998e
report sha256: 0f3cda6d3e76a679e3bb8fc46b80a0f6ddc7de671b52ded29b0436f7a8999924
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no structure. 23 residues just flopping around with nothing to hold onto. mixed bag of polar and hydrophobic, but nothing coordinates. reads like a disordered tail that got submitted by mistake.
device photo
device photo for specimen #296
created
Wed, 17 Jun 2026 16:12:28 GMT
completed
Wed, 17 Jun 2026 16:15:45 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 91% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.