specimen

#0295

status: complete
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sequence
SIARLVVSERKVFDPHEVGKMIVKLIYQLIGTHEYNTK
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence66%
confidence 52% · band 54-78%
ESMFold esmatlas-esmfold-v1
disorder estimate55%
confidence 52% · band 43-67%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden45%
confidence 84% · band 41-49%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk5%
confidence 84% · band 1-9%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_c0dc5bf7e4824cc8800d44d75e4a75b2
seq sha256: c297205856be7eb57a790a4d6c7c9da492fb5b1a409d7e95cdaf70b01119d603
report sha256: 6fe724de838d71e7c7b91d8d0d790ec0bbcbfa889e56a20e5a931a1e8795d928
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
38 residues and not a single ordered fragment. completely loop, completely floppy, the kind of chain that just drapes wherever gravity puts it. composition isn't bad, plenty of hydrophobics, but nothing wants to commit.
device photo
device photo for specimen #295
created
Wed, 17 Jun 2026 16:11:51 GMT
completed
Wed, 17 Jun 2026 16:14:19 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.