specimen

#0294

status: complete
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sequence
DKGKNRVLSIREEAFPLQVAQHATATGVVDPEIDLVPRGERLDNVL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence49%
confidence 52% · band 37-61%
ESMFold esmatlas-esmfold-v1
disorder estimate100%
confidence 52% · band 88-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden39%
confidence 84% · band 35-43%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk4%
confidence 84% · band 0-8%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk28%
confidence 56% · band 17-39%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_e16c5510b6554420915a3674126ad43a
seq sha256: fafd6419ef4d85fd2bfc24b28c6c6a44af61c98a36a9ac5ae2ae3980631633cd
report sha256: f15bbcfc513469c9c9a27eccf2e393fbdc93682fe68f7f7d5ab55f0ce6e71b03
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
46 residues of pure loop. no structure at all, just a long floppy ribbon doing nothing in particular. odd, because the composition isn't obviously disordered. should fold into something. doesn't.
device photo
device photo for specimen #294
created
Wed, 17 Jun 2026 16:11:16 GMT
completed
Wed, 17 Jun 2026 16:12:41 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 49% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.