specimen

#0293

status: complete
download JSONdownload PDFchat with report
sequence
WPETNLKQEREKRYAALPKYARLERSMTYFASGQYCPN
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence69%
confidence 52% · band 57-81%
ESMFold esmatlas-esmfold-v1
disorder estimate47%
confidence 52% · band 35-59%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden37%
confidence 84% · band 33-41%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk8%
confidence 84% · band 4-12%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_0d20ec1a011e4c6d9376d23556bfea4a
seq sha256: c2b908ccef76b237ec57e251e31461c3a4ed834c800fb828a55a4417f54865c8
report sha256: d1913b002b078785b64334112ce7b98dc4837f90d49ddbc678d5a3e8e9b0a5a4
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop. zero secondary structure, just 38 residues of pure conformational indecision. lots of charge in the middle though, arginines and glutamates packed together. probably wriggling more than folding.
device photo
device photo for specimen #293
created
Wed, 17 Jun 2026 16:10:39 GMT
completed
Wed, 17 Jun 2026 17:20:08 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.