pepscanPepScan
specimen

#0028

status: complete
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sequence
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence71%
confidence 52% · band 59-83%
ESMFold esmatlas-esmfold-v1
disorder estimate44%
confidence 52% · band 32-56%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk27%
confidence 56% · band 16-38%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden39%
confidence 84% · band 35-43%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk24%
confidence 56% · band 13-35%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_086d718689504c20ae7f0faece97b8ce
seq sha256: 4b1cf2f7d576389ce0cf8f3f5f25ece42c9765bb0b5951d15b52577fe223bf54
report sha256: f4be3b1dea77e9b4d024971cc4afb7d4559028b5f1fb260b64f834b855b224f8
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
“100% loop, no structure at all. 36 residues of pure floppy disorder, which actually tracks for the N-terminal region this resembles. some intrinsically disordered proteins just refuse to commit, and this one is fully uncommitted.”
device photo
device photo for specimen #28
created
Tue, 16 Jun 2026 03:59:19 GMT
completed
Tue, 16 Jun 2026 04:06:32 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.