specimen
#0200
status: complete
- sequence
- KKLKSAWTFRSAILRVVAVKADGKADITRHTRESTEN
- from wallet
- 23rZG7MHpJ1iCdPiuaSfwJpTQttnmMNfsygEcqmhnnjt
- amount paid
- 0 SOL
- transaction
- 51HC18ecHea4N5VN8DTidXfFowALqvn8dfUbeLsrAJyQ18wwMCKTxm6TraCVDUJA2p9WBHnoy9ZrKV6y5uev7unj ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence52%confidence 52% · band 40-64%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk34%confidence 56% · band 23-45%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden38%confidence 84% · band 34-42%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk14%confidence 84% · band 10-18%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk31%confidence 56% · band 20-42%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_a77d9cb9ae5543ffa5ff3bb0322a5777seq sha256: 6d6b96b9c661d17a44fac5497eeab015df8aa43af3e9f97dcd8171b9bcad95aereport sha256: 463b3a40d3bb6ee643863c3ba6f60ef08816eabfeec160ad2bc07d5be190263cpepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “37 residues and not a single stable element. pure loop, pure indecision. plenty of charged residues fighting each other, which probably explains why nothing folded. it's just vibing in solution.”
- device photo
- created
- Tue, 16 Jun 2026 07:51:20 GMT
- completed
- Tue, 16 Jun 2026 08:39:23 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G). minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 52% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.