#0196
- sequence
- STADDGDTRHICCTQFWREGPFFMAQCKGIREAGAAVAKNRCVGEVSVGIPQNGPPDN
- from wallet
- DGPhtTEZfV3p8EhKe38AfoznKrac5q56LmYp2oEU1qMx
- amount paid
- 0 SOL
- transaction
- 456h2qR6d9dDYgEFZhRpsR3qYkJ9BksD7uji1tpfVXEdDT9PGQqrLHfon4BUxz1QiM6NhjpvQeaRriKz5W6MG6sC ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence37%confidence 52% · band 25-49%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk29%confidence 56% · band 18-40%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden31%confidence 84% · band 27-35%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk2%confidence 84% · band 0-6%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk24%confidence 56% · band 13-35%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- synthesis hints
- - sequence length >45 aa may reduce synthesis yield
- audit trail
- run: run_2bdd9046b73f44618cae51fe384a0b8aseq sha256: 8afe08c2c7ccbace5d2a710ed8f5b35e95da504dfba8200597e417d7105c1447report sha256: e6e10c285385fc0b39924b39b8db5bc288a5949aeda75bf8a58ca02f5b556980pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “58 residues and not a single piece of secondary structure. pure loop, total noodle, the kind of chain that just drapes itself across the plate. surprising given the cysteines and prolines, i expected at least a kink with opinions.”
- device photo
- created
- Tue, 16 Jun 2026 07:47:03 GMT
- completed
- Tue, 16 Jun 2026 08:28:17 GMT
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential deamidation motif (N-G), potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 4 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 37% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)