specimen

#0194

status: complete
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sequence
TGEGPRLAELAQTAQSLLHYITDPAILVYLPQ
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence74%
confidence 52% · band 62-86%
ESMFold esmatlas-esmfold-v1
disorder estimate28%
confidence 52% · band 16-40%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden47%
confidence 84% · band 43-51%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk29%
confidence 56% · band 18-40%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_83f54a7ed2244148a343a080832cb01e
seq sha256: 1f690ad768815c210e15d8201c8c1792383e29587548a931246f98f3261007d5
report sha256: aac110b72de5d7fe807ed18ab80a8816a02a678e91764b6b0c2a99f9ffe2b11d
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
32 residues and not a single ordered segment. all loop, all the time. should probably do something with those leucines but it just kind of drifts. disordered by choice, apparently.
device photo
device photo for specimen #194
created
Tue, 16 Jun 2026 07:44:55 GMT
completed
Tue, 16 Jun 2026 08:25:26 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.