specimen
#0192
status: complete
- sequence
- FEIELLTRVVIDGTEGARLCSDDQVQEAVPPI
- from wallet
- DH3VMXx7FPxCuwBDTy7Q8YYP8KBv3RpqTZ4vQAQtvWyE
- amount paid
- 0 SOL
- transaction
- 3R7jtSdE74P1yJdoRYSCuqwjZ2a4iWTcS3U5Tjok4NcfeqNFoNynKQc14pCqKvm8y8SDv8jXMxFwctWsvskbgACv ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence56%confidence 52% · band 44-68%ESMFold esmatlas-esmfold-v1disorder estimate91%confidence 52% · band 79-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk34%confidence 56% · band 23-45%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden41%confidence 84% · band 37-45%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk16%confidence 84% · band 12-20%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_0e8981eff7f0496291fa6050b2f0aaf2seq sha256: 9938d97db888b6f977f2c890a05e9a91317aceb7152da0b7623ba5cdddde4825report sha256: 178bd2603b3a9afcb0c0e320b7a99acf48537f557a5165ad5a95f915936e0131pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “32 residues and not a single structured element. completely loop, completely floppy, the kind of chain that just drifts in solution waiting for a binding partner to tell it what to be. intrinsically disordered, probably on purpose.”
- device photo
- created
- Tue, 16 Jun 2026 07:42:47 GMT
- completed
- Tue, 16 Jun 2026 08:22:07 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G). minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 56% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 91% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.