#0190
- sequence
- SNTVFQLVVALEIAQILGVVDRYLFLECLPINVAESDGMMFRKALSGKEMQLVRMAS
- from wallet
- 7MwD77ZYhYzKLZ2cC3AKjEzCVFkHzbGuCzR4PsNAU3AV
- amount paid
- 0 SOL
- transaction
- 2393GSnjYMKTVQWwmuXnf6akZ4VXTED3jDXtEDn46xGyuZuuGSd6wBPMmqh6YenPXypZPr8L1tCfWqvaWEeszaVh ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence45%confidence 52% · band 33-57%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk40%confidence 56% · band 29-51%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden54%confidence 84% · band 50-58%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk2%confidence 84% · band 0-6%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk36%confidence 56% · band 25-47%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- synthesis hints
- - sequence length >45 aa may reduce synthesis yield
- audit trail
- run: run_f27deb181a644013b8d108893a8c997cseq sha256: 7145a65e4ce16a279f1a6b559c3fd76ae8947f3e9dcc8f43a57a455fba8d144creport sha256: d55a55f6693393be15ec5fda8f64ba2d37a0166989f6e185d7fa92d469ec0e85pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “57 residues and not a single ordered turn. completely loop, which is unusual for something this long with this much hydrophobic content. either it folds against something else or it's just refusing to commit.”
- device photo
- created
- Tue, 16 Jun 2026 07:40:40 GMT
- completed
- Tue, 16 Jun 2026 08:18:40 GMT
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 3 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 45% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)