specimen

#0187

status: complete
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sequence
LSLINDEKLGEDASFHSFDRRRPDYSCTSSAY
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence60%
confidence 52% · band 48-72%
ESMFold esmatlas-esmfold-v1
disorder estimate97%
confidence 52% · band 85-100%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk31%
confidence 56% · band 20-42%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden31%
confidence 84% · band 27-35%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk6%
confidence 84% · band 2-10%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk26%
confidence 56% · band 15-37%
PEPFOLD developability heuristic pepfold-triage-v1
developability flags
medium: structure confidence is limited
medium: predicted disorder is elevated
audit trail
run: run_4a40bba55d694d308a25406f84246bd2
seq sha256: 6fc6e2af0dd73f8abbf61fd4e5bd5fffac0498f0b18744f34a2b471fce53b5d8
report sha256: b7faa56ff80f9c3c4f4d07ddff8fdee0e663ab68470cb791de774c8a641b5840
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
100% loop. no structure at all, just 32 residues of pure indecision. the arginine cluster mid-sequence wants to do something but the rest of it refuses to commit.
device photo
device photo for specimen #187
created
Tue, 16 Jun 2026 07:37:29 GMT
completed
Tue, 16 Jun 2026 08:11:33 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. CD SPECTROSCOPY
    biophysical validation · 1–3d

    experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.

    trigger: fold_confidence 60% (model is uncertain)
  2. 2. 1H-15N HSQC
    biophysical validation · 2–5d

    if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.

    trigger: disorder_estimate 97% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.