specimen
#0183
status: complete
- sequence
- RETAYPHRTNVVPYGATAVLLRPSPLEIERRAVSTRMDV
- from wallet
- 92g1DJoHqrzNriKDM6RLyYDgNyCehujStfVpAvvSeQwF
- amount paid
- 0 SOL
- transaction
- NysZY7EEy8vDfQ84xXVxnPwErGQp3As5L9LTm9PHB8ZJuFDoJnNdDVnPJ3g3Pwgo8rppdwxbYv2vNgAQgkP52pQ ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence64%confidence 52% · band 52-76%ESMFold esmatlas-esmfold-v1disorder estimate74%confidence 52% · band 62-86%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk32%confidence 56% · band 21-43%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden41%confidence 84% · band 37-45%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk5%confidence 84% · band 1-9%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk28%confidence 56% · band 17-39%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_038f1f76b92545edb1947b9a49d9ecf9seq sha256: b89e1496e9bcc3f735aca2994b3b3d62f97db56b2ed1b0b77d2ad30fd86a2076report sha256: 6b1656f46116560a990782eec6534af14358b248484aeb7b65ffcda31252e17apepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no structure at all. 39 residues just drifting, no helix daring to form, no sheet trying its luck. reads like a disordered region that escaped from a larger protein and never found its way back.”
- device photo
- created
- Tue, 16 Jun 2026 07:33:14 GMT
- completed
- Tue, 16 Jun 2026 08:04:25 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 74% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.