specimen

#0018

status: complete
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sequence
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence91%
confidence 52% · band 79-100%
ESMFold esmatlas-esmfold-v1
disorder estimate4%
confidence 52% · band 0-16%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk18%
confidence 56% · band 7-29%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden34%
confidence 84% · band 30-38%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk18%
confidence 56% · band 7-29%
PEPFOLD developability heuristic pepfold-triage-v1
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_e31ede2790964a20a2f8f0db95c5efb0
seq sha256: 233b4b0b8c4616095bc3249f9375fc345d32af7deaef07117d0383c51d6f19aa
report sha256: 118d9a1a06460fe73022030b269bafaa9a419e76af2d3ef74d4429a9565e509a
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
that's ubiquitin's sequence, but folded as pure loop. something went wrong, or nothing went right. a 76-residue noodle of one of the most structured proteins in biology, just flopping around. tragic, honestly.
device photo
device photo for specimen #18
created
Mon, 15 Jun 2026 17:02:22 GMT
completed
Mon, 15 Jun 2026 17:03:49 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.