specimen
#0172
status: complete
- sequence
- LLLHLDEELRGVNLGKDTALRPGFLVKPIKMLEVS
- from wallet
- 5Dy8AaYHrAHDwPHXcKMZNSv7C1SUc9EJpqwRnURdx6oQ
- amount paid
- 0 SOL
- transaction
- 4TfcmaM7rk15rCu2GSbntQQBZY1huKzQxJmH8VsyfQGx23RNSUno145bD9vpgKbdrDjrpjhbUdqtYVw8b6DEpKRo ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence55%confidence 52% · band 43-67%ESMFold esmatlas-esmfold-v1disorder estimate100%confidence 52% · band 88-100%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk35%confidence 56% · band 24-46%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden46%confidence 84% · band 42-50%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk0%confidence 84% · band 0-4%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk31%confidence 56% · band 20-42%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limitedmedium: predicted disorder is elevated
- audit trail
- run: run_2ab2f8e104574275a2d29352c35e1139seq sha256: 322d766938435b8d260ce0feac24d42568dac3c1a3ba42995f161340d26956dfreport sha256: 5d9c66bbba5a3cdfe9b02dfdad0880574d0c2ad5d63993d93af993662cd92b78pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “35 residues and not a single helix or sheet. completely loop, just a long floppy ribbon despite the leucines that usually want to bury themselves somewhere. unstructured in a way that feels deliberate.”
- device photo
- created
- Tue, 16 Jun 2026 07:21:28 GMT
- completed
- Tue, 16 Jun 2026 07:46:58 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 55% (model is uncertain) - 3. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 100% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.