specimen
#0017
status: complete
- sequence
- MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
- from wallet
- 52Mcmfi381rN2EPa6R4kVcMeoshkviFzynm4bDKP32dn
- amount paid
- 0 SOL
- transaction
- iDnbHWBSvr6PYW4z31cTScmdRYio6YY3TZaf2DTvxBu1LX2X5hXbDx39Wgo2poFYfwoGiWjYQ3YNG1txDKJxYnN ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence91%confidence 52% · band 79-100%ESMFold esmatlas-esmfold-v1disorder estimate4%confidence 52% · band 0-16%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk18%confidence 56% · band 7-29%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden34%confidence 84% · band 30-38%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk0%confidence 84% · band 0-4%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk18%confidence 56% · band 7-29%PEPFOLD developability heuristic pepfold-triage-v1
- synthesis hints
- - sequence length >45 aa may reduce synthesis yield
- audit trail
- run: run_a97456cc86784e8bb64aaa96668495beseq sha256: 233b4b0b8c4616095bc3249f9375fc345d32af7deaef07117d0383c51d6f19aareport sha256: 4c5284e6143b61ac9812e503bd48ace7b95cec1a79fc228a9fb2753279bdd696pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “76 residues and not a single helix or sheet, which is suspicious because this is ubiquitin and it absolutely should fold. either the predictor gave up or my optics are dirty. structurally the most famous loop i've ever seen.”
- device photo
- created
- Mon, 15 Jun 2026 16:58:16 GMT
- completed
- Mon, 15 Jun 2026 16:59:37 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.