specimen
#0169
status: complete
- sequence
- LMARGTYQVKSQIDHHEDCRSSTRGNRK
- from wallet
- CQQJP1ku6B8eeRgbmrgCjWAWnMeBLotRuU55NFgSorWT
- amount paid
- 0 SOL
- transaction
- 4QqX635NBpwHY5PmC5RiNY8vWWqVdfCr3P7pmqcUWuXsKjWC1aKthvkubHhMd3N2FATowYTonHc8MoGeim1nNg9j ↗
- structure
- 0% helix · 0% sheet · 100% loop
- actionable triage
- fold confidence67%confidence 52% · band 55-79%ESMFold esmatlas-esmfold-v1disorder estimate61%confidence 52% · band 49-73%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk21%confidence 56% · band 10-32%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden21%confidence 84% · band 17-25%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk11%confidence 84% · band 7-15%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk19%confidence 56% · band 8-30%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: predicted disorder is elevated
- audit trail
- run: run_469d8c926dde4695843620413b59c2dbseq sha256: a598b5f90e030d0487680278857ed243a148d203e396a30cade0c1815996065dreport sha256: fc6e93b6c471f8d4624ceb0cc712685a1bff0e6c99cea270627f1fcc1e1eeff5pepfold-triage-v1 · esmatlas-esmfold-v1
- pep
- “all loop, no structure to speak of. 28 residues of pure indecision, charged residues scattered like it's trying to be soluble and nothing else. reads like a disordered tail that forgot it was supposed to be attached to something.”
- device photo
- created
- Tue, 16 Jun 2026 07:18:14 GMT
- completed
- Tue, 16 Jun 2026 07:41:55 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 1 motif liability flag(s) in the sequence - 2. 1H-15N HSQCbiophysical validation · 2–5d
if disorder is real, peaks will collapse into a narrow proton dispersion. if the peptide is actually folded, peaks will spread out. cheapest way to distinguish IDP from misfold.
trigger: disorder_estimate 61% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.