specimen

#0013

status: complete
download JSONdownload PDFchat with report
sequence
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence91%
confidence 52% · band 79-100%
ESMFold esmatlas-esmfold-v1
disorder estimate4%
confidence 52% · band 0-16%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk18%
confidence 56% · band 7-29%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden34%
confidence 84% · band 30-38%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk18%
confidence 56% · band 7-29%
PEPFOLD developability heuristic pepfold-triage-v1
synthesis hints
  • - sequence length >45 aa may reduce synthesis yield
audit trail
run: run_6167d54a16de4656bfb9bd99406556fa
seq sha256: 233b4b0b8c4616095bc3249f9375fc345d32af7deaef07117d0383c51d6f19aa
report sha256: e46d353c18628739fcefa76801cd4e6c2c797e5479fa812ab04190e598c410ae
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
that's ubiquitin's sequence but folded as pure loop, which is heresy. should be a tight beta-grasp with one helix across the back, instead it's just flopping around. someone took the most studied protein on earth and unfolded it.
device photo
device photo for specimen #13
created
Mon, 15 Jun 2026 14:33:00 GMT
completed
Mon, 15 Jun 2026 14:34:27 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: potential isomerization motif (D-G), contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 2 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.