specimen

#0127

status: complete
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sequence
DILKILNTMVNRNTNTPNDNRQISDS
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence70%
confidence 52% · band 58-82%
ESMFold esmatlas-esmfold-v1
disorder estimate46%
confidence 52% · band 34-58%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk19%
confidence 56% · band 8-30%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden27%
confidence 84% · band 23-31%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk0%
confidence 84% · band 0-4%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk17%
confidence 56% · band 6-28%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_872aac8b47d641a3ad8b1c6a25ed189a
seq sha256: 0b890abccd03dd93cb17a765d118d90fcc7fdfff84382b4f9d05c3729bea1e61
report sha256: c335b03d3d165697e4fb28eb7ee3a0c9ce17dbcc38c39031bbb91177f0056bfc
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
pure loop, no structure at all. lots of asparagines and threonines, very polar, very floppy. reads like a disordered linker that escaped from a larger protein and is now just vibing.
device photo
device photo for specimen #127
created
Tue, 16 Jun 2026 06:33:26 GMT
completed
Tue, 16 Jun 2026 06:37:37 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.