specimen
#0011
status: complete
- sequence
- MKWVTFISLLLLFSSAYS
- from wallet
- 7xKpAbCdEfGhIjKlMnOpQrStUvWxYz1234567nQ2
- amount paid
- 0.025 SOL
- transaction
- TEST_8b65367b99b1ad9db890c7c4ee151080 ↗
- structure
- 89% helix · 0% sheet · 11% loop
- actionable triage
- fold confidence1%confidence 78% · band 0-6%ESMFold esmatlas-esmfold-v1+fixturedisorder estimate46%confidence 78% · band 41-52%PEPFOLD structure heuristic pepfold-triage-v1aggregation risk47%confidence 74% · band 40-53%PEPFOLD developability heuristic pepfold-triage-v1hydrophobic burden67%confidence 84% · band 63-71%PEPFOLD sequence analyzer pepfold-triage-v1charge distribution risk6%confidence 84% · band 2-10%PEPFOLD sequence analyzer pepfold-triage-v1solubility risk43%confidence 74% · band 37-50%PEPFOLD developability heuristic pepfold-triage-v1
- developability flags
- medium: structure confidence is limited
- audit trail
- run: run_be20d2f75c9348579fa3c742ba5e957eseq sha256: 7d5253f399a813ea6d69a60f7358dbaee80cc3e46be43805f81eb76ce4bd0380report sha256: 555e063a46ff11aa054e9b9f38c2dcb2f0ea8fdddc7b9669ea0573cabb17fab9pepfold-triage-v1 · esmatlas-esmfold-v1+fixture
- pep
- “89% helix, signal-peptide vibes. hydrophobic as hell.”
- device photo
- created
- Tue, 02 Jun 2026 13:50:37 GMT
- completed
- Mon, 01 Jun 2026 00:00:00 GMT
next experiment
what to do next
deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.
- 1. LIABILITY REDESIGN ROUNDin silico only · 0–1d
redesign to remove the flagged motif(s) before going wet-lab: contains methionine; oxidation sensitivity possible, long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).
trigger: 2 motif liability flag(s) in the sequence - 2. CD SPECTROSCOPYbiophysical validation · 1–3d
experimental secondary structure check. confirms whether the predicted helix/sheet content matches a real spectrum before committing to higher-cost assays.
trigger: fold_confidence 1% (model is uncertain) - 3. SERUM STABILITY + SOLUBILITY CURVEbiophysical validation · 3–7d
track peptide concentration in 100% human serum over 0/1/4/24h; in parallel run a solubility titration in PBS. tells you whether the peptide survives long enough to act.
trigger: hydrophobic_burden 67% (high)
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.