specimen

#0103

status: failed
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sequence
NSVASGHENFGSAVAALEADSNL
amount paid
0 SOL
structure
0% helix · 0% sheet · 100% loop
actionable triage
fold confidence65%
confidence 52% · band 53-77%
ESMFold esmatlas-esmfold-v1
disorder estimate56%
confidence 52% · band 45-69%
PEPFOLD structure heuristic pepfold-triage-v1
aggregation risk34%
confidence 56% · band 23-45%
PEPFOLD developability heuristic pepfold-triage-v1
hydrophobic burden44%
confidence 84% · band 40-48%
PEPFOLD sequence analyzer pepfold-triage-v1
charge distribution risk13%
confidence 84% · band 9-17%
PEPFOLD sequence analyzer pepfold-triage-v1
solubility risk32%
confidence 56% · band 21-43%
PEPFOLD developability heuristic pepfold-triage-v1
audit trail
run: run_5298ff9627964665a88a6ecac6f1d48a
seq sha256: f31817c885dad7b5f17a78fb9d6ca01fac70e3841fc67e9d39ec55ad5bef55ac
report sha256: 37a687820be1c8a12c5f296b61c400f320d14379bea92d99815d0c4f6d32cdea
pepfold-triage-v1 · esmatlas-esmfold-v1
pep
all loop, no commitment. 23 residues of pure floppy disorder, not even a hint of secondary structure trying to form. the serines and glycines aren't helping, this thing just wants to drift.
device photo
device photo for specimen #103
created
Tue, 16 Jun 2026 05:46:13 GMT
next experiment

what to do next

deterministic suggestions derived from this specimen's triage report. each entry cites the signal that triggered it. ordered cheapest-first.

  1. 1. LIABILITY REDESIGN ROUND
    in silico only · 0–1d

    redesign to remove the flagged motif(s) before going wet-lab: long hydrophobic run may increase aggregation risk. minimal substitutions usually suffice (e.g. N→Q for deamidation hotspots, M→L for met oxidation).

    trigger: 1 motif liability flag(s) in the sequence
engine pepfold-recs-v1 · not medical advice. use as a starting point for protocol design.